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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
14.55
Human Site:
S546
Identified Species:
21.33
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
S546
K
S
I
D
D
V
D
S
K
L
K
G
I
G
K
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
M606
G
S
L
P
P
A
A
M
E
S
M
E
S
L
R
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
S546
N
S
V
D
D
V
D
S
K
L
K
G
I
G
K
Dog
Lupus familis
XP_545291
1075
123911
S547
K
S
V
D
D
M
D
S
K
L
K
G
I
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
M546
K
I
V
D
E
T
D
M
K
L
K
G
I
G
K
Rat
Rattus norvegicus
P70496
1074
123795
M546
K
S
V
N
D
T
D
M
K
L
K
G
I
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
S545
A
D
D
V
P
D
I
S
K
M
K
G
I
G
K
Frog
Xenopus laevis
NP_001129642
1039
119219
T521
N
K
I
P
S
D
P
T
L
S
L
N
G
D
N
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
I503
T
R
S
V
A
Q
A
I
E
Q
G
L
D
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
T792
P
P
P
D
E
P
N
T
S
I
E
L
K
T
L
Honey Bee
Apis mellifera
XP_001121004
1135
129725
T574
T
N
T
V
V
M
A
T
T
K
S
I
P
V
L
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
R855
K
N
K
K
E
L
R
R
A
V
T
S
L
E
R
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
Q336
R
A
K
Q
A
R
N
Q
N
G
S
L
G
H
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
I514
I
G
D
C
P
P
Y
I
W
P
G
K
D
Y
Y
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
F731
P
V
K
G
N
Q
G
F
R
I
D
R
M
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
6.6
86.6
86.6
N.A.
66.6
73.3
N.A.
0
46.6
6.6
0
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
26.6
93.3
100
N.A.
80
86.6
N.A.
0
53.3
13.3
6.6
N.A.
40
20
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
13
7
19
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
13
32
25
13
32
0
0
0
7
0
13
7
0
% D
% Glu:
0
0
0
0
19
0
0
0
13
0
7
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
7
0
0
7
0
0
7
13
38
13
38
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
7
13
0
0
0
7
13
0
13
0
7
38
0
0
% I
% Lys:
32
7
19
7
0
0
0
0
38
7
38
7
7
0
44
% K
% Leu:
0
0
7
0
0
7
0
0
7
32
7
19
7
13
13
% L
% Met:
0
0
0
0
0
13
0
19
0
7
7
0
7
0
0
% M
% Asn:
13
13
0
7
7
0
13
0
7
0
0
7
0
0
13
% N
% Pro:
13
7
7
13
19
13
7
0
0
7
0
0
7
0
0
% P
% Gln:
0
0
0
7
0
13
0
7
0
7
0
0
0
0
0
% Q
% Arg:
7
7
0
0
0
7
7
7
7
0
0
7
0
0
13
% R
% Ser:
0
32
7
0
7
0
0
25
7
13
13
7
7
7
7
% S
% Thr:
13
0
7
0
0
13
0
19
7
0
7
0
0
7
0
% T
% Val:
0
7
25
19
7
13
0
0
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _